San Diego, California – September, 2020. Medicinal chemists at the Human BioMolecular Research Institute (HBRI), in San Diego, CA, and biologists at Sanford-Burnham-Prebys Medical Discovery Institute (SBPMDI), in San Diego, CA, and at Stanford University, Stanford, CA, Columbia University, New York, NY, and Northwestern University, Chicago, IL, respectively, have reported on improving an antiarrhythmic drug using patient-derived human induced pluripotent stem cell cardiomyocytes (hiPSC-CMs) in a high throughput manner in vitro. This may have importance for heart disease and other drug discovery efforts.
https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(20)30399-4
